- Emily Murphy, 1931
- The Ursuline Nuns establish a school for girls in Quebec.
- First hospital in Canada, Hôtel-Dieu in Montreal, is opened by Jeanne Mance.
- First Francophone female writer born in Canada - Marie Morin
- First school teacher in Montreal, arrives from France - Marguerite Bourgeoys.
- 775 French orphan girls and young women are sent to New France under the banner "Filles du roi" to marry settlers.
- First English woman to come to James Bay, Mrs. (John) Sargeant, wife of the Governor of the Hudson Bay Company, with her companion Mrs. Maurice, and a maidservant.
- Marguerite d'Youville founds the Grey Nuns order in Montreal.
- First Jewish woman to arrive in Canada - Esther Brandeau (in the guise of a cabin boy).
- First Canadian printing office and Canada's first newspaper, the weekly Halifax Gazette - Elizabeth Bushell (with her father).
- First recorded female art teacher in Montréal, Quebec - Jeanne Charlotte Allamand.
- First work of fiction by a native born Canadian to be published in Canada - Julia Catherine Hart.
- First female professional photographer - Mrs. (John) Fletcher (portrait studio in Montreal).
- Women in Ontario got the right to vote for school trustees if they owned property regardless of marital status.
- Susanna Moodie published Roughing It in the Bush about life as a pioneer in then Upper Canada.
- First woman publisher in Canada - Mary Shadd Carey
- First black woman publisher in North America (The Provincial Freeman, 1853 to 1857) - Mary Shadd Carey
- First university in Canada to admit women — Mount Allison in New Brunswick (did not include the right to study in professional faculties).
- First woman doctor in Canada - Emily Stowe (her practice was in Toronto but her training was in the States
- First female doctor to graduate from a Canadian Medical School - Dr. Augusta Stowe-Gullen
- First woman to teach at a Canadian medical school - Dr. Augusta Stowe-Gullen (she helped found the Toronto Western Hospital with her husband Dr. John B. Gullen)
- First woman lawyer in Ontario, Canada and the British Empire - Clara Brett Martin
- Creation of the world's first Women's Institute - Adelaide Hunter (Hoodless) in Stoney Creek, Ontario (she also introduced the teaching of domestic science into Ontario schools)
- First Canadian woman nuclear physicist — Harriet Brooks (she was also the first woman to obtain a Master's Degree from McGill in 1901)
- First woman intern at Toronto General Hospital - Dr. Helen MacMurchy (named one of the western world's leading physicians in 1949)
- First francophone woman to practice medicine in Canada - Irma Levasseur (she co-founded Sainte-Justine Hospital in Montréal)
- Women admitted to the University of Toronto's Faculty of Medicine for the first time
- First single woman to be granted homestead rights in Ontario - Dorothea Mitchell (Canada’s first female independent film maker)
- First woman in the British Empire to become a judge - Emily Murphy
- Women obtained the right to vote in a federal election
- First election including female candidates
- First Canadian woman to be a member of Parliament - Agnes Macphail (also one of the first two women elected to Ontario Legislature)
- Ada McKenzie founded the Ladies’ Golf Club of Toronto, the first private golf club in North America owned and operated by women
- First Canadian woman to earn a degree in electrical engineering - Elsie MacGill (University of Toronto)
- Canadian women are allowed to compete in the Olympic Games for the first time.
- First woman senator - Cairine Wilson
- First female CGA in Canada - Ivy A. Cox
- First woman to be elected a mayor in Canada (in Webbwood, Ontario) - Barbara McCallum Hanley
- First woman corporate member to the Engineering Institute of Canada - Elsie MacGill
- First woman to become a colonel in the Canadian Army - Elizabeth Laurie Smellie
- First woman to be given the title of official war artist (World War II) - Molly Lamb Bobak
- First "Woman Mountie", the RCMP's first Honourary Surgeon - Dr. Francis McGill
- First woman to head a provincial party - Thérèse Forget Casgrain (in the province of Québec)
- First woman federal cabinet minister - Ellen Fairclough
- First woman appointed ambassador for Canada - Blanche Margaret Meagher (posted in Israel)
- First Canadian woman to be named Minister of Health and Welfare - Judy LaMarsh (she introduced the Canada Pension Plan and established the Royal Commission on the Status of Women)
- First women professional golfer in Canada - Sandra Post
- First woman president of the physical sciences section of the Royal Society of Canada and the first female president of the Royal Canadian Institute - Helen Hogg
- First woman physician president of the Ontario Medical Association - Dr. Bette Stephenson
- First solo exhibition at the National Gallery of Canada of the work of a living Canadian woman - Joyce Wieland
- First black woman elected to a legislature in Canada (B.C.) - Rosemary Brown
- First woman candidate for the leadership of a major Canadian political party (NDP) - Rosemary Brown
- First North American woman airline pilot - Rosella Bjornson
- First woman president of the Canadian Medical Association - Dr. Bette Stephenson
- First female Lieutenant-Governor in the British Commonwealth - Pauline McGibbon (of Ontario)
- The RCMP begins to accept women in their ranks.
- First woman to lead a major national union in Canada - Grace Hartman (CUPE)
- First president of the Fédération des francophones hors Québec founded in 1975 (which later became the Fédération des communautés francophones et acadienne du Canada (FCFA) in June 1991) - Jeannine Séguin
- Troop 17 was the first group of 32 females accepted into the RCMP. This first all-female troop graduated from Depot on March 3, 1975.
- Carolyn Bowes became the first woman to run across Canada. It took 133 days to cover the 3,840 miles from Halifax, Nova Scotia to Burnaby, British Columbia.
- First woman Speaker of the House of Commons – Jeanne Sauvé
- First woman minister responsible for the Status of Women in Parliament - Judy Erola
- First woman on the Supreme Court - Bertha Wilson
- First Canadian woman officially recognized as a saint (canonized) - Marguerite Bourgeoys (founder of the Congrégation de Notre-Dame de Montréal)
- First woman Governor General - Jeanne Sauvé
- First black person ever appointed to the Canadian Senate - Anne Cools
- First televised debate on women's issues between the three major federal parties - organized by National Action Committee on the Status of Women
- First North American woman to scale Mount Everest - Sharon Wood of Canmore, Alberta
- First woman president of the Canadian Labour Congress - Shirley Carr
- First francophone woman appointed to the Supreme Court of Canada - Claire L'Heureux-Dubé
- First woman federal party leader - Audrey McLaughlin
- First female pilots in the world to sucessfully complete and qualify to fly the CF18 Jet Fighter Aircraft - Deanna Brasseur and Jane Foster
- First woman deputy Speaker of the House of Commons - Andrée Champagne
- First Women's World Hockey Championships won by Canada
- First Military female aircraft accident investigator - Deanna Brasseur
- First woman Premier of a province - Rita Johnston (B.C.)
- First Canadian Woman in Space - Roberta Bondar (second Canadian astronaut to go into space)
- First female President of the Canadian Bar Association - Paule Gauthier, Quebec City lawyer
- October is proclaimed Women's History Month in Canada by the Government of Canada.
- First woman Prime Minister - Kim Campbell
- First woman to be named Leader of the Government in the Senate - Joyce Fairbairn
- First black woman elected to the House of Commons - Jean Augustine
- First woman deputy prime minister - Sheila Copps
- First woman Chief Justice of the Supreme Court of Canada - Beverley McLachlin
- First female Premier of a territory (Yukon) - Pat Duncan
- First woman appointed Auditor General of Canada - Sheila Fraser
- First Canadian to win five medals at a single Olympic Winter Games - Cindy Klasssen.
- First woman appointed Commander of the Royal Canadian Mounted Police - Bev Busson.
- First female to occupy top anchor spot (chef d’antenne) at the Télévision de Radio-Canada, Céline Galipeau, Le Téléjournal.
- First Canadian Member of Parliament for the Green Party - Elizabeth May.
- First woman in Canada appointed as Chief of Reserves and Cadets - Rear Admiral Jennifer Bennett.
- First full-time female anchor in one of the three major English-language national newscasts - Lisa LaFlamme, CTV National News.
- First female doctor to receive the Patient's Choice Award, given in June 2012 by the Patient's Association of Canada and the Ontario Medical Association - Dr. Evelyn Honsl who practices in Ottawa